Across TCGA patient cohorts, ENPP1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,349 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ENPP1-associated genes across cancer lineages are MYL9, MEIS3, and SGIP1. Each is linked with ENPP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ENPP1-to-partner and partner-to-ENPP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP1→partner) and Y-score (partner→ENPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.515	+0.662	<.001	<.001	3	8
UCEC	MEIS3 →	+1.195	+0.674	<.001	<.001	3	8
LSCC	SGIP1 →	+1.023	+0.899	<.001	<.001	3	8
OV	DACT3 →	+0.874	+0.784	<.001	<.001	3	8
HNSC	UBE2QL1 →	+0.761	+0.762	<.001	<.001	3	8
OV	COL10A1 →	+2.977	+0.976	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,349 associations by consensus.

Exploration

ENPP1 survival (RNA) · tumor vs normal (RNA) · all ENPP1 data types