ENOX1

Across TCGA patient cohorts, ENOX1 mutation is significantly associated with the RNA expression of many other genes, with 3,303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENOX1-associated genes across cancer lineages are NUS1, CKAP2L, and KIF23. Each is linked with ENOX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ENOX1-to-partner and partner-to-ENOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUS1 grouped by ENOX1-low versus ENOX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOX1→partner) and Y-score (partner→ENOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUS1 →	+0.410	+2.343	.001	<.001	3	4
LUAD	CKAP2L →	+0.755	+3.712	.009	<.001	3	4
LUAD	KIF23 →	+0.795	+3.477	.007	.002	3	4
LUAD	GTSE1 →	+0.907	+3.339	.001	.005	3	3
UCEC	NUFIP1 →	+0.408	+2.479	<.001	.001	3	3
UCEC	EI24 →	+0.429	+2.050	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,303 associations by consensus.

NUS1 by ENOX1 expression — UCEC

Explore this box plot interactively →