ENOX1

Across TCGA patient cohorts, ENOX1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENOX1-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2K, and MEK1. Each is linked with ENOX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ENOX1-to-partner and partner-to-ENOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ENOX1-low versus ENOX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOX1→partner) and Y-score (partner→ENOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.501	+1.505	.010	.034	3	3
LUSC	eEF2K →	+0.484	+3.009	.006	.019	3	2
UCEC	MEK1 →	+0.342	+2.087	.004	.005	3	2
UCEC	mTOR_pS2448 →	-0.110	-1.745	.025	.013	3	2
UCEC	p27_pT198 →	+0.081	+1.906	.021	.015	3	2
UCEC	p70-S6K_pT389 →	-0.154	-2.584	.014	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Caspase-7-cleavedD198 by ENOX1 expression — UCEC

Explore this box plot interactively →