ENOX1

Across TCGA cell cohorts, ENOX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,824 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ENOX1-associated GO terms across cancer lineages are Vacuolar transmembrane transport, Mitotic cell cycle phase transition, and Regulation of smoothened signaling pathway. Each is linked with ENOX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ENOX1-to-partner and partner-to-ENOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transmembrane transport grouped by ENOX1-low versus ENOX1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOX1→partner) and Y-score (partner→ENOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Vacuolar transmembrane transport →	-0.143	-0.539	<.001	<.001	3	7
OESOPHAGUS	Mitotic cell cycle phase transition →	+0.058	+0.772	.007	.009	2	8
STOMACH	Regulation of smoothened signaling pathway →	+0.054	+1.052	<.001	.004	3	7
LARGE_INTESTINE	Attachment of GPI anchor to protein →	+0.131	+0.640	<.001	.001	3	7
STOMACH	Calcium-independent cell-cell adhesion →	-0.277	-0.919	<.001	.002	3	7
BONE	Positive regulation of early endosome to late endosome transport →	+0.132	+1.115	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,824 associations by consensus.

Vacuolar transmembrane transport by ENOX1 expression — BLOOD_Leukemia

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