ENOSF1

Across TCGA pan-cancer cohorts, ENOSF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ENOSF1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ENOSF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ENOSF1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, HNSC, and LUAD are the cancer types where ENOSF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.952	0.824	.021	16	view →
HNSC	DFS	Quartile	II,III,IV	0.894	0.975	.017	8	view →
LUAD	OS	Quartile	II,III,IV	0.467	0.802	.037	4	view →
PDAC	DFS	Median	III,IV	0.493	0.934	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ENOSF1–UCEC (DFS)

Open the UCEC breakdown →