ENOPH1

Across TCGA patient cohorts, ENOPH1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENOPH1-associated genes across cancer lineages are aDC, CD8+ T-cells, and CD8+ Tcm. Each is linked with ENOPH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENOPH1-to-partner and partner-to-ENOPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by ENOPH1-low versus ENOPH1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOPH1→partner) and Y-score (partner→ENOPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.109	+3.031	.002	.018	3	1
UCEC	CD8+ T-cells →	+0.034	+2.675	<.001	.007	3	1
UCEC	CD8+ Tcm →	+0.043	+2.765	<.001	.005	3	1
UCEC	CD8+ Tem →	+0.003	+4.481	<.001	.047	3	1
UCEC	Macrophages →	+0.030	+2.913	<.001	<.001	3	1
UCEC	Macrophages M1 →	+0.030	+2.158	<.001	.022	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

aDC by ENOPH1 expression — UCEC

Explore this box plot interactively →