Across TCGA cell cohorts, ENO4 mutation is significantly associated with the RNA expression of many other genes, with 330 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENO4-associated genes across cancer lineages are ANKRD54, CBY1, and EIF3D. Each is linked with ENO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENO4-to-partner and partner-to-ENO4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO4→partner) and Y-score (partner→ENO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD54 →	+0.526	+3.299	.003	.004	3	1
LARGE_INTESTINE	CBY1 →	+0.800	+3.299	<.001	.004	3	1
LARGE_INTESTINE	EIF3D →	+0.516	+3.307	.001	.003	3	1
LARGE_INTESTINE	PRMT5 →	+0.701	+3.212	<.001	.006	3	1
LARGE_INTESTINE	GUCY2F →	+0.007	+2.688	<.001	.002	3	1
LARGE_INTESTINE	TNFRSF10A →	+0.900	+3.299	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 330 associations by consensus.

Exploration

ENO4 survival (RNA) · tumor vs normal (RNA) · all ENO4 data types