ENO3

Across TCGA cell cohorts, ENO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,113 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ENO3-associated GO terms across cancer lineages are Regulation of telomere maintenance, Telomere maintenance, and Positive regulation of monoatomic ion transport. Each is linked with ENO3 in more than 10 cancer types. Because this analysis shows association rather than direction, both ENO3-to-partner and partner-to-ENO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by ENO3-low versus ENO3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO3→partner) and Y-score (partner→ENO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.078	+1.960	<.001	<.001	3	11
BLOOD_Leukemia	Telomere maintenance →	+0.048	+0.816	.001	.003	3	11
URINARY_TRACT	Positive regulation of monoatomic ion transport →	-0.118	-1.507	<.001	.001	3	11
BLOOD_Leukemia	Negative regulation of telomere maintenance via telomere lengthening →	+0.072	+1.298	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.085	+3.055	<.001	<.001	3	10
URINARY_TRACT	Telomere organization →	+0.070	+1.561	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,113 associations by consensus.

Regulation of telomere maintenance by ENO3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →