ENO2

Across TCGA patient cohorts, ENO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,069 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ENO2-associated proteins across cancer lineages are PLOD2, SLC2A1, and LOXL2. Each is linked with ENO2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ENO2-to-partner and partner-to-ENO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENO2 versus PLOD2 in PDAC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO2→partner) and Y-score (partner→ENO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLOD2 →	+1.037	+1.097	<.001	<.001	3	9
LSCC	SLC2A1 →	+0.912	+1.028	<.001	<.001	3	8
PDAC	LOXL2 →	+1.082	+1.066	<.001	<.001	3	8
PDAC	P4HA1 →	+0.838	+1.113	<.001	<.001	3	8
PDAC	PLOD1 →	+0.632	+1.003	<.001	<.001	3	7
GBM	IL16 →	-0.558	-0.611	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,069 associations by consensus.

ENO2 vs PLOD2 — PDAC

Explore this scatter interactively →