ENO2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ENO2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ENO2-associated genes across cancer lineages are IQCF5. Each is linked with ENO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENO2-to-partner and partner-to-ENO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by ENO2-low versus ENO2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO2→partner) and Y-score (partner→ENO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaIQCF5 →+0.121+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

IQCF5 by ENO2 expression — BLOOD_Leukemia

Box plot of IQCF5 in ENO2-low vs ENO2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration