ENKD1

Across TCGA pan-cancer cohorts, ENKD1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ENKD1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ENKD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ENKD1 expression acts as an unfavorable survival marker.

LUAD, HNSC, and CCRCC are the cancer types where ENKD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.729	0.961	.013	10	view →
HNSC	OS	Median	All	0.255	0.762	.025	8	view →
CCRCC	OS	Median	II,III,IV	0.622	1.000	.020	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ENKD1–LUAD (DFS)

Open the LUAD breakdown →