ENKD1

Across TCGA patient cohorts, ENKD1 mutation is significantly associated with the RNA expression of many other genes, with 801 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENKD1-associated genes across cancer lineages are RN7SKP232, RNU4-26P, and RNU6-591P. Each is linked with ENKD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENKD1-to-partner and partner-to-ENKD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP232 grouped by ENKD1-low versus ENKD1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENKD1→partner) and Y-score (partner→ENKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP232 →	+0.157	+4.588	<.001	.008	3	2
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	2
STAD	RNU6-591P →	+0.396	+4.396	<.001	.002	3	2
UCEC	RNA5SP424 →	+0.188	+2.782	.005	.004	3	2
UCEC	SNORD126 →	+0.392	+2.418	<.001	.005	3	2
SKCM	DHFRP3 →	+0.052	+4.680	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 801 associations by consensus.

RN7SKP232 by ENKD1 expression — BLCA

Explore this box plot interactively →