ENGASE

Across TCGA cell cohorts, ENGASE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,179 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ENGASE-associated GO terms across cancer lineages are mRNA splice site recognition, Viral translational termination-reinitiation, and Negative regulation of DNA-templated transcription initiation. Each is linked with ENGASE in more than 14 cancer types. Because this analysis shows association rather than direction, both ENGASE-to-partner and partner-to-ENGASE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by ENGASE-low versus ENGASE-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENGASE→partner) and Y-score (partner→ENGASE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA splice site recognition →	+0.180	+1.812	.001	.001	3	15
SOFT_TISSUE	Viral translational termination-reinitiation →	+0.077	+0.995	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated transcription initiation →	+0.111	+1.363	.001	.007	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription elongation by RNA polymerase II →	+0.146	+1.493	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Microtubule nucleation →	+0.108	+1.853	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription initiation by RNA polymerase II →	+0.111	+1.363	.001	.007	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,179 associations by consensus.

mRNA splice site recognition by ENGASE expression — OESOPHAGUS

Explore this box plot interactively →