ENDOV

Across TCGA patient cohorts, ENDOV mutation is significantly associated with the RNA expression of many other genes, with 4,517 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENDOV-associated genes across cancer lineages are MIR548X, ARF4P1, and TAF9. Each is linked with ENDOV in more than 2 cancer types. Because this analysis shows association rather than direction, both ENDOV-to-partner and partner-to-ENDOV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR548X grouped by ENDOV-low versus ENDOV-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENDOV→partner) and Y-score (partner→ENDOV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR548X →	+0.465	+7.471	<.001	.008	3	3
UCEC	ARF4P1 →	+0.419	+2.254	<.001	.001	3	2
UCEC	TAF9 →	+0.765	+3.000	<.001	<.001	3	2
UCEC	UHRF1 →	+1.080	+2.332	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.458	+1.782	<.001	.001	3	2
COAD	RPS6P7 →	+0.204	+4.478	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,517 associations by consensus.

MIR548X by ENDOV expression — BRCA

Explore this box plot interactively →