ENDOD1

Across TCGA pan-cancer cohorts, ENDOD1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ENDOD1 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ENDOD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ENDOD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, CCRCC, and GBM are the cancer types where ENDOD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.692	0.892	.006	12	view →
CCRCC	OS	Tertile	III,IV	0.830	0.534	.031	2	view →
GBM	DFS	Quartile	All	0.613	0.840	.018	1	view →
HNSC	OS	Median	IV	0.635	0.830	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ENDOD1–PDAC (DFS)

Open the PDAC breakdown →