ENDOD1

Across TCGA cell cohorts, ENDOD1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENDOD1-associated genes across cancer lineages are EPPIN, RASGEF1C, and OR10W1. Each is linked with ENDOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENDOD1-to-partner and partner-to-ENDOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by ENDOD1-low versus ENDOD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENDOD1→partner) and Y-score (partner→ENDOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
LARGE_INTESTINE	RASGEF1C →	+0.196	+3.555	.009	.003	3	1
LARGE_INTESTINE	OR10W1 →	+0.009	+3.240	<.001	.004	3	1
LARGE_INTESTINE	ACSM6 →	+0.020	+3.000	<.001	.005	3	1
LARGE_INTESTINE	IQCF6 →	+0.181	+2.882	<.001	.005	3	1
LARGE_INTESTINE	CD300H →	+0.027	+3.678	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

EPPIN by ENDOD1 expression — BLOOD_Leukemia

Explore this box plot interactively →