ENC1

Across TCGA cell cohorts, ENC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,674 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ENC1-associated GO terms across cancer lineages are Regulation of epithelial cell migration, Rho protein signal transduction, and Epithelial cell development. Each is linked with ENC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ENC1-to-partner and partner-to-ENC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of epithelial cell migration grouped by ENC1-low versus ENC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENC1→partner) and Y-score (partner→ENC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of epithelial cell migration →	+0.093	+2.065	<.001	.001	3	11
BONE	Rho protein signal transduction →	+0.135	+3.141	<.001	<.001	3	11
BONE	Epithelial cell development →	+0.133	+3.012	<.001	<.001	3	11
BONE	Integrin-mediated signaling pathway →	+0.250	+2.861	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to membrane →	+0.059	+1.564	.001	.004	3	10
KIDNEY	Positive regulation of epithelial cell migration →	+0.143	+1.816	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,674 associations by consensus.

Regulation of epithelial cell migration by ENC1 expression — BONE

Explore this box plot interactively →