ENAM

Across TCGA cell cohorts, ENAM RNA expression is significantly associated with the go_rna of many other GO terms, with 1,476 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ENAM-associated GO terms across cancer lineages are Regulation of neutrophil apoptotic process, Positive regulation of neutrophil apoptotic process, and Artery smooth muscle contraction. Each is linked with ENAM in more than 4 cancer types. Because this analysis shows association rather than direction, both ENAM-to-partner and partner-to-ENAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of neutrophil apoptotic process grouped by ENAM-low versus ENAM-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENAM→partner) and Y-score (partner→ENAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of neutrophil apoptotic process →	-0.112	-0.545	.003	.007	3	5
BLOOD_Leukemia	Positive regulation of neutrophil apoptotic process →	-0.112	-0.545	.003	.007	3	5
BLOOD_Lymphoma	Artery smooth muscle contraction →	+1.131	+0.753	<.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of DNA-templated transcription, elongation →	+0.055	+0.612	.001	.005	3	4
BLOOD_Lymphoma	Positive regulation of enamel mineralization →	-0.153	-0.785	<.001	<.001	3	4
LUNG_SCLC	Negative regulation of cellular response to growth factor stimulus →	-0.069	-0.521	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,476 associations by consensus.

Regulation of neutrophil apoptotic process by ENAM expression — BLOOD_Leukemia

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