ENAH

Across TCGA cell cohorts, ENAH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,800 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ENAH-associated GO terms across cancer lineages are Actin polymerization-dependent cell motility, Nucleic acid transport, and RNA transport. Each is linked with ENAH in more than 16 cancer types. Because this analysis shows association rather than direction, both ENAH-to-partner and partner-to-ENAH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin polymerization-dependent cell motility grouped by ENAH-low versus ENAH-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENAH→partner) and Y-score (partner→ENAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Actin polymerization-dependent cell motility →	+0.187	+1.558	<.001	<.001	3	17
PANCREAS	Nucleic acid transport →	+0.102	+1.973	<.001	<.001	3	16
PANCREAS	RNA transport →	+0.102	+1.973	<.001	<.001	3	16
PANCREAS	Establishment of RNA localization →	+0.094	+1.782	<.001	.001	3	15
OESOPHAGUS	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.182	+1.131	.002	.006	3	15
STOMACH	RNA export from nucleus →	+0.106	+1.991	.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,800 associations by consensus.

Actin polymerization-dependent cell motility by ENAH expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →