EN2

Across TCGA patient cohorts, EN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EN2-associated proteins across cancer lineages are DDX18, RBM28, and MYBBP1A_S1308. Each is linked with EN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EN2-to-partner and partner-to-EN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EN2 versus DDX18 in LSCC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EN2→partner) and Y-score (partner→EN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDX18 →	+0.301	+0.430	<.001	<.001	3	3
BRCA	RBM28 →	+0.334	+0.623	.009	<.001	3	3
LSCC	MYBBP1A_S1308 →	+0.740	+0.559	.005	.001	3	3
LUAD	ITGA6 →	-0.337	-0.206	.001	.003	3	3
GBM	TNS1 →	-0.335	-0.872	<.001	<.001	3	3
LSCC	MTX2 →	+0.179	+0.580	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,919 associations by consensus.

EN2 vs DDX18 — LSCC

Explore this scatter interactively →