EN2

Across TCGA patient cohorts, EN2 protein abundance is significantly associated with the RNA expression of many other genes, with 273 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EN2-associated genes across cancer lineages are LRRC74A, RIN3, and NFATC2. Each is linked with EN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EN2-to-partner and partner-to-EN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EN2 versus LRRC74A in UCEC, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EN2→partner) and Y-score (partner→EN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRC74A →	-0.542	-2.086	<.001	.003	3	1
UCEC	RIN3 →	-0.914	-2.140	.007	.004	3	1
UCEC	NFATC2 →	-0.878	-2.471	.002	<.001	3	1
UCEC	SPINT3 →	-1.853	-2.393	<.001	.008	3	1
UCEC	PRPS2 →	+1.147	+1.918	<.001	.008	3	1
UCEC	MSLN →	-4.046	-2.935	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 273 associations by consensus.

EN2 vs LRRC74A — UCEC

Explore this scatter interactively →