EN1

Across TCGA patient cohorts, EN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,032 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EN1-associated proteins across cancer lineages are SULF1, FN1, and HTRA3. Each is linked with EN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EN1-to-partner and partner-to-EN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EN1 versus SULF1 in CCRCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EN1→partner) and Y-score (partner→EN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SULF1 →	+1.188	+0.278	<.001	<.001	3	5
OV	FN1 →	+0.814	+0.143	<.001	<.001	3	5
COAD	HTRA3 →	+0.869	+0.210	<.001	<.001	3	5
COAD	RCN3 →	+0.736	+0.214	<.001	<.001	3	5
BRCA	SERPINH1 →	+0.648	+1.792	<.001	<.001	3	5
OV	SPARC →	+0.733	+0.191	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,032 associations by consensus.

EN1 vs SULF1 — CCRCC

Explore this scatter interactively →