EN1

Across TCGA cell cohorts, EN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,515 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible EN1-associated GO terms across cancer lineages are Embryonic brain development, Negative regulation of endodermal cell differentiation, and Acetylcholine biosynthetic process. Each is linked with EN1 in more than 10 cancer types. Because this analysis shows association rather than direction, both EN1-to-partner and partner-to-EN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic brain development grouped by EN1-low versus EN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EN1→partner) and Y-score (partner→EN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Embryonic brain development →	-0.158	-1.332	.002	<.001	3	11
STOMACH	Negative regulation of endodermal cell differentiation →	+1.035	+0.303	<.001	.009	3	8
BREAST	Acetylcholine biosynthetic process →	-0.910	-1.880	.001	<.001	3	7
BONE	Elastin metabolic process →	+0.248	+1.373	.002	<.001	3	7
SOFT_TISSUE	Embryonic skeletal joint morphogenesis →	-0.217	-0.768	<.001	.003	3	7
BREAST	Positive regulation of podosome assembly →	+1.149	+2.569	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,515 associations by consensus.

Embryonic brain development by EN1 expression — BONE

Explore this box plot interactively →