EMX2

Across TCGA cell cohorts, EMX2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EMX2-associated genes across cancer lineages are OR13C5, SULT6B1, and S100A7A. Each is linked with EMX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMX2-to-partner and partner-to-EMX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C5 grouped by EMX2-low versus EMX2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMX2→partner) and Y-score (partner→EMX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR13C5 →	+0.760	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	SULT6B1 →	+0.025	+3.714	.002	.006	3	1
BLOOD_Lymphoma	S100A7A →	+0.021	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	A3GALT2 →	+0.031	+4.606	<.001	.001	3	1
BLOOD_Lymphoma	PPP3R2 →	+0.027	+4.196	<.001	.002	3	1
LARGE_INTESTINE	VAX1 →	+0.774	+3.519	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR13C5 by EMX2 expression — URINARY_TRACT

Explore this box plot interactively →