EMSY

Across TCGA patient cohorts, EMSY protein abundance is significantly associated with the RNA expression of many other genes, with 14,210 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EMSY-associated genes across cancer lineages are CDON, THAP12, and CREBZF. Each is linked with EMSY in more than 6 cancer types. Because this analysis shows association rather than direction, both EMSY-to-partner and partner-to-EMSY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMSY versus CDON in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMSY→partner) and Y-score (partner→EMSY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDON →	+0.883	+0.322	.008	.004	3	7
LSCC	THAP12 →	+0.954	+0.317	<.001	<.001	3	6
HNSC	CREBZF →	+0.514	+0.196	.001	.002	3	6
BRCA	DBF4B →	+0.656	+0.275	<.001	<.001	3	6
GBM	GVQW3 →	+0.572	+0.345	<.001	<.001	3	6
HNSC	MRE11 →	+0.660	+0.283	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,210 associations by consensus.

EMSY vs CDON — GBM

Explore this scatter interactively →