EMSY

Across TCGA cell cohorts, EMSY RNA expression is significantly associated with the go_rna of many other GO terms, with 4,789 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EMSY-associated GO terms across cancer lineages are Centrosome cycle, Microtubule organizing center organization, and Centriole replication. Each is linked with EMSY in more than 18 cancer types. Because this analysis shows association rather than direction, both EMSY-to-partner and partner-to-EMSY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by EMSY-low versus EMSY-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMSY→partner) and Y-score (partner→EMSY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.094	+0.862	.002	.009	3	19
LUNG_NSCLC_LUSC	Microtubule organizing center organization →	+0.095	+0.950	.001	.002	3	19
BONE	Centriole replication →	+0.130	+0.626	<.001	<.001	3	18
BONE	Centrosome duplication →	+0.107	+0.629	<.001	<.001	3	18
BONE	Regulation of microtubule-based process →	+0.051	+0.701	.001	<.001	3	17
LARGE_INTESTINE	Microtubule polymerization or depolymerization →	+0.097	+0.804	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,789 associations by consensus.

Centrosome cycle by EMSY expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →