Across TCGA cell cohorts, EMP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,686 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EMP2-associated GO terms across cancer lineages are Natural killer cell proliferation, Heart formation, and T cell mediated cytotoxicity. Each is linked with EMP2 in more than 15 cancer types. Because this analysis shows association rather than direction, both EMP2-to-partner and partner-to-EMP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMP2→partner) and Y-score (partner→EMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Natural killer cell proliferation →	+0.933	+1.854	<.001	.003	2	16
KIDNEY	Heart formation →	+0.223	+1.634	.004	<.001	3	10
LUNG_NSCLC_LUAD	T cell mediated cytotoxicity →	+0.203	+1.520	<.001	<.001	3	9
LARGE_INTESTINE	Protein localization to cell surface →	+0.138	+1.021	<.001	.002	3	9
URINARY_TRACT	Positive regulation of integrin-mediated signaling pathway →	+0.210	+2.062	<.001	<.001	3	8
PANCREAS	Response to molecule of fungal origin →	+1.172	+1.846	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,686 associations by consensus.

Exploration

EMP2 survival (RNA) · tumor vs normal (RNA) · all EMP2 data types