EMP1

Across TCGA patient cohorts, EMP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,987 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EMP1-associated proteins across cancer lineages are ZNF446_S3, WDHD1_S383, and WDR75. Each is linked with EMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMP1-to-partner and partner-to-EMP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMP1 versus ZNF446_S3 in CCRCC, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EMP1→partner) and Y-score (partner→EMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZNF446_S3 →	+0.310	+0.571	<.001	.002	3	1
HNSC	WDHD1_S383 →	-0.700	-0.758	.002	.002	3	1
HNSC	WDR75 →	-0.450	-0.795	.002	.001	3	1
HNSC	WNK1_S1978 →	+1.286	+0.805	.005	.001	3	1
HNSC	WNK1_S2230 →	+1.286	+0.805	.005	.001	3	1
HNSC	WNK1_S2286 →	+1.618	+1.072	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,987 associations by consensus.

EMP1 vs ZNF446_S3 — CCRCC

Explore this scatter interactively →