EMP1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EMP1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMP1-associated genes across cancer lineages are CD8+ naive T-cells and Myocytes. Each is linked with EMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMP1-to-partner and partner-to-EMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by EMP1-low versus EMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMP1→partner) and Y-score (partner→EMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD8+ naive T-cells →+0.034+3.212.022.01031
UCECMyocytes →+0.038+3.212.034.01021
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ naive T-cells by EMP1 expression — UCEC

Box plot of CD8+ naive T-cells in EMP1-low vs EMP1-high samples in UCEC.

Explore this box plot interactively →

Exploration