EMP1

Across TCGA cell cohorts, EMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,166 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EMP1-associated GO terms across cancer lineages are Bleb assembly, Positive regulation of chemotaxis, and Negative regulation of actin filament depolymerization. Each is linked with EMP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both EMP1-to-partner and partner-to-EMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bleb assembly grouped by EMP1-low versus EMP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMP1→partner) and Y-score (partner→EMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Bleb assembly →	+0.737	+2.733	.003	.002	3	15
OESOPHAGUS	Positive regulation of chemotaxis →	+0.143	+2.743	.008	.002	3	13
BONE	Negative regulation of actin filament depolymerization →	+0.210	+4.267	<.001	<.001	3	13
PANCREAS	Blood coagulation, intrinsic pathway →	+0.406	+3.833	<.001	<.001	3	12
BONE	Regulation of protein localization to membrane →	+0.080	+3.420	.001	.005	3	12
LUNG_SCLC	Activation of blood coagulation via clotting cascade →	+0.522	+1.511	.009	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,166 associations by consensus.

Bleb assembly by EMP1 expression — LUNG_SCLC

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