Across TCGA patient cohorts, EML6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,950 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EML6-associated proteins across cancer lineages are RNF213, VDAC1, and TRIM21. Each is linked with EML6 in more than 3 cancer types. Because this analysis shows association rather than direction, both EML6-to-partner and partner-to-EML6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EML6→partner) and Y-score (partner→EML6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNF213 →	-0.482	-0.701	<.001	<.001	3	4
CCRCC	VDAC1 →	-0.362	-0.678	<.001	<.001	3	4
GBM	TRIM21 →	-0.363	-0.469	.006	.007	3	4
LSCC	HNRNPLL →	+0.242	+0.616	<.001	<.001	3	3
HNSC	IFIT3 →	-0.734	-0.531	<.001	<.001	3	3
LSCC	ISG20 →	-0.572	-0.685	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,950 associations by consensus.

Exploration

EML6 survival (RNA) · tumor vs normal (RNA) · all EML6 data types