Across TCGA patient cohorts, EML6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,335 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EML6-associated genes across cancer lineages are WNK4, GDI2P2, and PHACTR3-AS1. Each is linked with EML6 in more than 1 cancer types. Because this analysis shows association rather than direction, both EML6-to-partner and partner-to-EML6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EML6→partner) and Y-score (partner→EML6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	WNK4 →	-0.454	-0.789	<.001	.001	3	2
GBM	GDI2P2 →	+0.825	+0.308	.002	<.001	3	2
GBM	PHACTR3-AS1 →	+0.899	+0.272	.003	.001	3	2
GBM	BTBD10P1 →	+0.064	+0.269	.003	<.001	3	2
GBM	DOC2B →	+1.144	+0.355	<.001	<.001	3	2
LUAD	PSMB3 →	-0.600	-1.178	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,335 associations by consensus.

Exploration

EML6 survival (RNA) · tumor vs normal (RNA) · all EML6 data types