Across TCGA patient cohorts, EML6 mutation is significantly associated with the RNA expression of many other genes, with 3,244 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EML6-associated genes across cancer lineages are ALKBH1, MTMR4, and HSPA9. Each is linked with EML6 in more than 2 cancer types. Because this analysis shows association rather than direction, both EML6-to-partner and partner-to-EML6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EML6→partner) and Y-score (partner→EML6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALKBH1 →	+0.241	+1.615	.003	.001	3	3
UCEC	MTMR4 →	+0.269	+1.197	.007	.002	3	3
COAD	HSPA9 →	+0.341	+3.342	.004	.005	3	3
UCEC	C12orf65 →	+0.237	+1.716	.001	.003	3	3
UCEC	GCH1 →	+0.493	+1.117	<.001	.007	3	3
UCEC	LARP1B →	+0.417	+2.112	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,244 associations by consensus.

Exploration

EML6 survival (RNA) · tumor vs normal (RNA) · all EML6 data types