Across TCGA cell cohorts, EML6 mutation is significantly associated with the RNA expression of many other genes, with 1,013 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EML6-associated genes across cancer lineages are VPS37D, UFSP2, and KCTD1. Each is linked with EML6 in more than 3 cancer types. Because this analysis shows association rather than direction, both EML6-to-partner and partner-to-EML6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EML6→partner) and Y-score (partner→EML6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	VPS37D →	+0.978	+3.243	<.001	.006	3	3
LARGE_INTESTINE	UFSP2 →	+0.534	+3.082	.001	.007	3	3
LARGE_INTESTINE	KCTD1 →	+1.159	+3.743	<.001	<.001	2	4
LARGE_INTESTINE	ADO →	+0.464	+3.330	<.001	.002	3	3
LARGE_INTESTINE	CD300H →	+0.015	+2.540	<.001	.007	3	3
LARGE_INTESTINE	ACTR6 →	+0.700	+3.829	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,013 associations by consensus.

Exploration

EML6 survival (RNA) · tumor vs normal (RNA) · all EML6 data types