EML6-AS1

Across TCGA pan-cancer cohorts, EML6-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated EML6-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher EML6-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EML6-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and COAD show a favorable association.

BLCA, CHOL, and THCA are the cancer types where EML6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.297	0.557	.001	111	view →
CHOL	DFS	Tertile	All	0.100	0.496	.006	63	view →
THCA	OS	Tertile	IV	0.626	1.000	.002	57	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
UCEC	DFS	Tertile	All	0.642	0.844	.005	30	view →
READ	DFS	Tertile	III,IV	0.059	0.761	<.001	18	view →
BRCA	DFS	Tertile	All	0.278	0.537	.024	18	view →
ESCA	DFS	Quartile	III,IV	0.528	0.277	.030	9	view →
PAAD	OS	Tertile	All	0.430	0.646	.046	9	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →
ACC	DFS	Quartile	All	0.281	0.631	.013	8	view →
COAD	OS	Tertile	All	0.965	0.789	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

EML6-AS1–BLCA (DFS)

Open the BLCA breakdown →