EML4

Across TCGA patient cohorts, EML4 RNA expression is significantly associated with the RNA expression of many other genes, with 20,834 significant associations in total. UVM shows the largest number of these associations.

The most reproducible EML4-associated genes across cancer lineages are CDK12, MAP3K2, and BPTF. Each is linked with EML4 in more than 33 cancer types. Because this analysis shows association rather than direction, both EML4-to-partner and partner-to-EML4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EML4 versus CDK12 in DLBC, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EML4→partner) and Y-score (partner→EML4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	CDK12 →	+1.143	+1.269	<.001	<.001	3	34
UVM	MAP3K2 →	+1.539	+1.121	<.001	<.001	3	34
UVM	BPTF →	+1.374	+1.227	<.001	<.001	3	34
DLBC	HELZ →	+1.221	+1.341	<.001	<.001	3	34
DLBC	BAZ2A →	+1.489	+1.346	<.001	<.001	3	34
UVM	INTS2 →	+1.262	+1.132	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,834 associations by consensus.

EML4 vs CDK12 — DLBC

Explore this scatter interactively →