EML4

Across TCGA patient cohorts, EML4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,251 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EML4-associated proteins across cancer lineages are EML4_S138, HNRNPLL, and PPM1G. Each is linked with EML4 in more than 4 cancer types. Because this analysis shows association rather than direction, both EML4-to-partner and partner-to-EML4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EML4 versus EML4_S138 in BRCA, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EML4→partner) and Y-score (partner→EML4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EML4_S138 →	+0.953	+0.654	.005	.001	3	5
HNSC	HNRNPLL →	+0.311	+0.747	<.001	<.001	3	4
GBM	PPM1G →	+0.384	+0.296	<.001	.004	3	4
BRCA	EML4_S146 →	+0.423	+0.454	<.001	.003	3	4
OV	RPL4 →	-0.335	-0.570	.001	<.001	3	3
BRCA	MRPS36 →	-0.478	-0.647	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,251 associations by consensus.

EML4 vs EML4_S138 — BRCA

Explore this scatter interactively →