EML2

Across TCGA patient cohorts, EML2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,670 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EML2-associated proteins across cancer lineages are CHMP2A, AP1M2, and ARMCX1. Each is linked with EML2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EML2-to-partner and partner-to-EML2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EML2 versus CHMP2A in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EML2→partner) and Y-score (partner→EML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CHMP2A →	+0.266	+0.285	<.001	<.001	3	4
LSCC	AP1M2 →	+0.424	+0.550	<.001	<.001	3	4
UCEC	ARMCX1 →	-0.652	-0.464	<.001	<.001	3	4
PDAC	PPP5C →	+0.214	+0.333	<.001	<.001	3	4
BRCA	PNKP →	+0.319	+0.861	<.001	<.001	3	4
COAD	PKP4 →	+0.402	+0.626	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,670 associations by consensus.

EML2 vs CHMP2A — PDAC

Explore this scatter interactively →