EML2

Across TCGA patient cohorts, EML2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,474 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EML2-associated genes across cancer lineages are HELLS, PLCG1, and MCM8. Each is linked with EML2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EML2-to-partner and partner-to-EML2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EML2 versus HELLS in UCEC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EML2→partner) and Y-score (partner→EML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HELLS →	-0.663	-0.275	<.001	<.001	3	7
COAD	PLCG1 →	-0.825	-0.228	<.001	.004	3	7
HNSC	MCM8 →	-0.593	-0.339	.005	<.001	3	7
BRCA	TROAP →	-1.115	-0.655	<.001	<.001	3	7
LSCC	EME1 →	-0.750	-0.321	<.001	<.001	3	7
UCEC	PLK1 →	-0.820	-0.500	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,474 associations by consensus.

EML2 vs HELLS — UCEC

Explore this scatter interactively →