EML2

Across TCGA cell cohorts, EML2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,853 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EML2-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Negative regulation of protein polymerization, and Response to purine-containing compound. Each is linked with EML2 in more than 13 cancer types. Because this analysis shows association rather than direction, both EML2-to-partner and partner-to-EML2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by EML2-low versus EML2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EML2→partner) and Y-score (partner→EML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of protein-containing complex assembly →	+0.091	+1.167	.005	.002	3	14
PANCREAS	Negative regulation of protein polymerization →	+0.123	+0.883	<.001	.003	3	12
OESOPHAGUS	Response to purine-containing compound →	+0.090	+1.561	<.001	<.001	3	11
URINARY_TRACT	Membrane depolarization during bundle of His cell action potential →	+1.355	+1.853	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Response to forskolin →	+0.179	+1.013	.001	.002	3	11
PANCREAS	Cellular response to unfolded protein →	+0.098	+0.948	.002	.005	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,853 associations by consensus.

Negative regulation of protein-containing complex assembly by EML2 expression — OESOPHAGUS

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