EML2-AS1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EML2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,259 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EML2-AS1-associated GO terms across cancer lineages are mRNA 3'-splice site recognition, Regulation of protein oligomerization, and Ribosome assembly. Each is linked with EML2-AS1 in more than 10 cancer types. Because this analysis shows association rather than direction, both EML2-AS1-to-partner and partner-to-EML2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-splice site recognition grouped by EML2-AS1-low versus EML2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EML2-AS1→partner) and Y-score (partner→EML2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAmRNA 3'-splice site recognition →+0.044+0.094.001<.001311
LIHCRegulation of protein oligomerization →+0.039+0.046<.001<.001310
STADRibosome assembly →+0.039+0.062<.001<.00139
ESCAChaperone-mediated protein folding →+0.064+0.098.001<.00138
STADMitochondrial translation →+0.037+0.052<.001<.00138
ESCAMitochondrial respiratory chain complex assembly →+0.039+0.064.002<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,259 associations by consensus.

mRNA 3'-splice site recognition by EML2-AS1 expression — ESCA

Box plot of mRNA 3'-splice site recognition in EML2-AS1-low vs EML2-AS1-high samples in ESCA.

Explore this box plot interactively →

Exploration