EML1

Across TCGA patient cohorts, EML1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,934 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EML1-associated genes across cancer lineages are TSPAN18, PTH1R, and NEGR1. Each is linked with EML1 in more than 8 cancer types. Because this analysis shows association rather than direction, both EML1-to-partner and partner-to-EML1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EML1 versus TSPAN18 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EML1→partner) and Y-score (partner→EML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TSPAN18 →	+1.126	+0.413	<.001	.001	3	9
CCRCC	PTH1R →	+1.443	+0.397	<.001	.001	3	9
CCRCC	NEGR1 →	+0.936	+0.446	.004	<.001	3	9
BRCA	TCEAL7 →	+1.073	+0.356	<.001	<.001	3	9
BRCA	LHFPL6 →	+1.112	+0.370	<.001	<.001	3	9
UCEC	CXCL12 →	+1.327	+0.554	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,934 associations by consensus.

EML1 vs TSPAN18 — OV

Explore this scatter interactively →