EMILIN1

Across TCGA patient cohorts, EMILIN1 mutation is significantly associated with the RNA expression of many other genes, with 4,415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMILIN1-associated genes across cancer lineages are NEIL2, RNU6-947P, and TLE6. Each is linked with EMILIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EMILIN1-to-partner and partner-to-EMILIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEIL2 grouped by EMILIN1-low versus EMILIN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMILIN1→partner) and Y-score (partner→EMILIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NEIL2 →	+0.529	+2.700	<.001	<.001	3	3
LUAD	RNU6-947P →	+0.241	+5.000	<.001	.003	3	3
UCEC	TLE6 →	+0.579	+1.737	.003	.002	3	3
UCEC	IGLVI-38 →	+0.082	+1.845	.001	.005	3	3
UCEC	COX15 →	+0.561	+2.321	<.001	<.001	3	2
UCEC	SLC7A11 →	+0.735	+2.818	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,415 associations by consensus.

NEIL2 by EMILIN1 expression — UCEC

Explore this box plot interactively →