EME1

Across TCGA pan-cancer cohorts, EME1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EME1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher EME1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated EME1 expression acts as an unfavorable survival marker.

LSCC, HNSC, and UCEC are the cancer types where EME1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	III,IV	0.771	1.000	.034	6	view →
HNSC	OS	Median	All	0.823	0.944	.019	5	view →
UCEC	DFS	Quartile	All	0.883	1.000	.026	4	view →
LUAD	DFS	Tertile	All	0.635	1.000	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EME1–LSCC (DFS)

Open the LSCC breakdown →