EME1

Across TCGA patient cohorts, EME1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,643 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EME1-associated genes across cancer lineages are FOXM1, NEK2, and KIF2C. Each is linked with EME1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EME1-to-partner and partner-to-EME1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EME1 versus FOXM1 in LUAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EME1→partner) and Y-score (partner→EME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FOXM1 →	+1.105	+0.909	.004	.003	3	5
BRCA	NEK2 →	+1.090	+0.527	<.001	<.001	3	5
BRCA	KIF2C →	+1.021	+0.490	<.001	<.001	3	5
LUAD	IQGAP3 →	+1.958	+0.870	<.001	.006	3	5
LUAD	RDM1 →	+0.981	+0.947	<.001	.002	3	5
LUAD	RAD54L →	+1.317	+0.915	<.001	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,643 associations by consensus.

EME1 vs FOXM1 — LUAD

Explore this scatter interactively →