EME1

Across TCGA cell cohorts, EME1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,591 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EME1-associated GO terms across cancer lineages are Cell cycle DNA replication, Meiotic cell cycle, and DNA-templated DNA replication. Each is linked with EME1 in more than 19 cancer types. Because this analysis shows association rather than direction, both EME1-to-partner and partner-to-EME1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle DNA replication grouped by EME1-low versus EME1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EME1→partner) and Y-score (partner→EME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cell cycle DNA replication →	+0.151	+1.306	<.001	<.001	3	20
BONE	Meiotic cell cycle →	+0.101	+1.466	.006	.005	3	20
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.157	+1.666	<.001	<.001	3	20
BONE	Double-strand break repair →	+0.076	+1.347	.002	.001	3	20
URINARY_TRACT	Response to cell cycle checkpoint signaling →	+0.141	+1.462	<.001	<.001	3	20
BONE	Double-strand break repair via homologous recombination →	+0.107	+1.654	.002	.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,591 associations by consensus.

Cell cycle DNA replication by EME1 expression — LIVER

Explore this box plot interactively →