EMD

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EMD RNA expression is significantly associated with the protein abundance of many other proteins, with 11,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EMD-associated proteins across cancer lineages are PCNA, NSDHL, and FAM50A. Each is linked with EMD in more than 4 cancer types. Because this analysis shows association rather than direction, both EMD-to-partner and partner-to-EMD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMD versus PCNA in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EMD→partner) and Y-score (partner→EMD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPCNA →+0.468+0.379.001.00935
LUADNSDHL →+0.479+0.594<.001<.00135
OVFAM50A →+0.545+0.539<.001.00135
LUADHTATSF1 →+0.345+0.696<.001<.00135
LUADPGRMC1 →+0.478+0.439.001.00135
BRCAPLEKHO1_S227 →-0.776-0.557.006<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,261 associations by consensus.

EMD vs PCNA — OV

Per-sample scatter of EMD vs PCNA in OV (Pearson r = 0.33).

Explore this scatter interactively →

Exploration