EMC9

Across TCGA cell cohorts, EMC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,938 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EMC9-associated GO terms across cancer lineages are Protein linear polyubiquitination, Regulation of cell cycle checkpoint, and Protein insertion into ER membrane by stop-transfer membrane-anchor sequence. Each is linked with EMC9 in more than 15 cancer types. Because this analysis shows association rather than direction, both EMC9-to-partner and partner-to-EMC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by EMC9-low versus EMC9-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC9→partner) and Y-score (partner→EMC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein linear polyubiquitination →	+0.207	+1.254	.001	<.001	3	16
KIDNEY	Regulation of cell cycle checkpoint →	+0.078	+0.732	.009	.007	2	12
URINARY_TRACT	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.130	+0.954	.001	.008	3	11
UPPER_AERODIGESTIVE_TRACT	Meiotic cell cycle →	+0.098	+1.059	<.001	<.001	3	11
SOFT_TISSUE	Chromosome condensation →	+0.175	+0.997	<.001	<.001	3	10
BONE	Pericentric heterochromatin formation →	+0.146	+0.746	.002	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,938 associations by consensus.

Protein linear polyubiquitination by EMC9 expression — URINARY_TRACT

Explore this box plot interactively →