EMC8

Across TCGA patient cohorts, EMC8 protein abundance is significantly associated with the RNA expression of many other genes, with 10,880 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EMC8-associated genes across cancer lineages are YPEL2, C19orf44, and ARHGEF6. Each is linked with EMC8 in more than 4 cancer types. Because this analysis shows association rather than direction, both EMC8-to-partner and partner-to-EMC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC8 versus YPEL2 in BRCA, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC8→partner) and Y-score (partner→EMC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YPEL2 →	-0.616	-0.161	<.001	<.001	3	5
UCEC	C19orf44 →	-0.547	-0.164	<.001	<.001	3	4
BRCA	ARHGEF6 →	-0.618	-0.158	<.001	<.001	3	4
OV	COX4I1 →	+0.576	+0.217	<.001	<.001	3	4
BRCA	PIEZO2 →	-1.226	-0.249	<.001	<.001	3	4
CCRCC	SHROOM4 →	-0.544	-0.183	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,880 associations by consensus.

EMC8 vs YPEL2 — BRCA

Explore this scatter interactively →