EMC6

Across TCGA patient cohorts, EMC6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,775 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EMC6-associated genes across cancer lineages are MARCHF8, ZFAND4, and POLI. Each is linked with EMC6 in more than 2 cancer types. Because this analysis shows association rather than direction, both EMC6-to-partner and partner-to-EMC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC6 versus MARCHF8 in BRCA, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC6→partner) and Y-score (partner→EMC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MARCHF8 →	-0.726	-0.421	.005	.008	3	3
BRCA	ZFAND4 →	-1.082	-0.687	<.001	<.001	3	3
BRCA	POLI →	-0.931	-0.486	.001	.003	3	3
OV	ZSCAN26 →	-0.508	-0.418	.002	<.001	3	3
BRCA	SEPSECS →	-0.753	-0.503	.004	.002	3	2
HNSC	RPL39P5 →	-1.124	-0.557	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,775 associations by consensus.

EMC6 vs MARCHF8 — BRCA

Explore this scatter interactively →